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Amyloid protein stability analysis
Enter PDB ID
Enter FASTA sequence
Analyzing Protein..
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CreateFibril
STEP 1: SELECT AN AMYLOID PROTEIN
Enter PDB ID
GET
STEP 2: POLYMORPHISM TYPE
Polymorphism
Single
Stack
Ring
Polygon
Parameters for Single structure:
Fibril axis direction vector TIP:
Store point
Parameters for Stack structure:
Fibril axis direction vector:
Store initial point
Store final point
Strand vector:
Store initial point
Store final point
Number of protofibrils:
2
Radius between protofibrils (Å):
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
Parameters for Polygon structure:
Fibril axis direction vector:
Store initial point
Store final point
Strand vector:
Store initial point
Store final point
Number of protofibrils:
3
4
Radius between protofibrils (Å):
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
Parameters for Ring structure:
Strand vector:
Store initial point
Store final point
Number of protofibrils:
2
3
4
Radius between protofibrils (Å):
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
STEP 3: STRUCTURAL PARAMETERS
Monomer angle of rotation:
-30
-29
-28
-27
-26
-25
-24
-23
-22
-21
-20
-19
-18
-17
-16
-15
-14
-13
-12
-11
-10
-9
-8
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
Distance between aggregates (Å):
0.0
2.0
3.0
4.0
4.1
4.2
4.3
4.4
4.5
4.6
4.7
4.8
4.9
5.0
5.1
5.2
5.3
5.4
5.5
7.0
10.0
15.0
No. of aggregate repetitions:
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
CreateFibril
Fibril Mutant
MAPOR
SEMBA
© 2025 Mohamed Raef Smaoui
